بررسی میزان اثربخشی واکسن سینوفارم در گروه سنی ۲۱ تا ۲۱سال
کد: G-1110
نویسندگان: Owrang Eilami ℗, Maryam Alavi ©, Hosein Mostafavi
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Introduction The study addresses the need for real-world data on the effectiveness of the Sinopharm vaccine in reducing the severity of COVID-19 infections, complications, ICU admissions, and mortality among 12 to 18-year-olds in Shiraz, Iran. This research is crucial for health policy-making, especially since serious illness and death from COVID-19, although rare in children, do occur. Material and Method A retrospective cohort study was conducted using HIS data from Shiraz hospitals (Shahid Faghihi, Namazi, Ali Asghar) for children aged 12 to 18 who were infected with SARS-CoV-2 between August 21, 2021, and February 19, 2022. Data collected included age, gender, PCR test results, symptom onset date, hospitalization dates, and duration of stay in the ward or ICU. Additional information was gathered through questionnaires. Results ● Participants: 711 children (average age 15.12 ± 2.03 years; 52.9% boys). ● Vaccination Status: 55.4% non-immunized, 44.6% fully immunized. ● Hospitalization: The hospitalization rate in the immunized group was significantly lower (25.7%) than in the non-immunized group, with a vaccine effectiveness of 52% in preventing hospitalization. ● Mortality: 16 children (2.3%) died, indicating a 59% effectiveness of the Sinopharm vaccine in preventing deaths among the vaccinated group compared to the non-vaccinated group. Conclusion and Discussion Despite the overall lower risk of severe illness and death from COVID-19 in children, the results underscore the importance of vaccination in this age group to mitigate the impact of the virus. The data supports the continued use of the Sinopharm vaccine in adolescents to reduce the burden on healthcare systems and improve public health outcomes. Further research is recommended to monitor long-term effectiveness and potential side effects of the vaccine in this population
کلمات کلیدی
Sinopharm vaccine ,vaccine effectiveness, adolescents
