بررسی اپیدمیولوژیک و شناسایی عوامل ویروسی عفونت حاد تنفسی در کودکان بستری در بیمارستان افضلیپور کرمان، زمستان و بهار 1402-1403
کد: G-1112
نویسندگان: Ali Hosseininasab ℗, Nahid Raeisi, Niloofar Farsiu, Reza Sinaei, Atiyeh Shokrian, Javad Charostad, Mohammad Pardeshenas, Mohsen Nakhaie ©
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Background and Objective: Acute respiratory infections (ARIs) are a leading cause of morbidity and mortality in children, particularly in developing countries. This study aimed to conduct an epidemiological investigation and identify the viral agents responsible for ARIs in hospitalized children at Afzalipour Hospital during the winter and spring of 1402-1403. Methods: This cross-sectional study was conducted on 100 children diagnosed with ARI. Samples from the oropharynx and nasopharynx were collected from patients and transferred to the virology department. DNA extraction was performed for adenovirus, and RNA extraction was conducted for SARS-CoV-2, influenza A and B, and RSV. Nested-PCR was used to identify adenovirus, while Real-Time PCR was employed for RNA viruses. Data were analyzed using SPSS version 20 and logistic regression tests. Results: Among the collected samples, 22% were positive for RSV, 14% for influenza A, 3% for influenza B, 3% for adenovirus, and 9% for SARS-CoV-2. Data analysis indicated that certain clinical and demographic characteristics were significantly associated with the presence of viruses. Notably, being younger than 5 years and having a history of underlying conditions were significantly related to the presence of RSV and influenza A. Additionally, children infected with SARS-CoV-2 were more likely to live in urban areas and had a higher percentage of previous viral infections. Conclusion: This study demonstrated that RSV and influenza A were the predominant agents causing ARI in children, with certain demographic and clinical characteristics, such as age and underlying conditions, playing a crucial role in increasing the likelihood of infection by these viruses. Identifying these viral agents and associated characteristics can be beneficial for clinical management and prevention of ARI in children. Further research is recommended to examine viral patterns and their impacts on public health.
کلمات کلیدی
Children, respiratory infections, SARS-CoV-2 virus, influenza A, influenza B, respiratory syncytial virus, adenovirus
