تاثیر یک رژیم غذایی کم FODMAP و پروبیوتیک ها بر درمان سندرم روده تحریک پذیر: یک مرور سیستماتیک

Yasamin Ahmadi ℗, Ali Jamshidi, Marziye Doraghi, Amir Mohammad Chekeni ©

تاثیر یک رژیم غذایی کم FODMAP و پروبیوتیک ها بر درمان سندرم روده تحریک پذیر: یک مرور سیستماتیک

کد: G-1123

نویسندگان: Yasamin Ahmadi ℗, Ali Jamshidi, Marziye Doraghi, Amir Mohammad Chekeni ©

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خلاصه مقاله

Introduction: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder that presents with symptoms like abdominal pain, bloating, and altered bowel movements. Traditional treatments often fail to provide adequate relief, leading to increased interest in complementary approaches such as the low-FODMAP diet and probiotics. The low-FODMAP diet aims to alleviate symptoms by restricting fermentable carbohydrates that are difficult to digest, thereby reducing bloating and abdominal discomfort. Conversely, probiotics enhance gut health by balancing the gut microbiome, reducing inflammation, and boosting immune function. This review aims to evaluate the efficacy of these strategies in alleviating IBS symptoms and improving patients' quality of life. Method: A systematic review was performed independently by two people based on the PICO criteria and aligned to the research objective and based on the PRISMA checklist and using PubMed, Medline, Cochrane, Sciencedirect, SID databases Google Scholar search engine, and Boolean operators. The time limit between 2019 and 2024 was determined using the MESH keywords " FODMAP Diet”, “Probiotics “ and “Irritable Bowel Syndrome”. After checking the entry and exit criteria and critically evaluating the quality of the selected articles, a total of 7 articles were included in the study. Results: Comprehensive analyzes showed that the low-FODMAP diet was significantly associated with reduced abdominal pain (30-50% on average) and bloating (40-60%). Also, a decrease in fermentation and an improvement in the speed of gastrointestinal emptying were observed in these patients. Probiotics, especially Bifidobacterium and Lactobacillus strains, helped improve gut function and reduce gastrointestinal symptoms by increasing microbiome diversity and decreasing inflammatory markers such as IL-6 and TNF-α. The combination of these two methods showed synergistic effects that led to a stronger reduction in clinical symptoms. Conclusion: This observe suggests that the combination of low FODMAP food regimen and probiotics may be an powerful way to manage IBS signs and symptoms. But, in addition studies are had to determine extra powerful probiotic lines and to optimize the diet. Future studies should look at personalized processes and lengthy-time period outcomes to attain greater effective treatments.

کلمات کلیدی

Irritable Bowel Syndrome, FODMAP Diet , Probiotics

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