فراوانی باکتری های شایع عامل مننژیتیس در نمونه های مایع مغزی نخاعی به روش کشت و PCR در استان همدان
کد: G-1016
نویسندگان: Amjad Ahmadi, Mohsen Nazari, Jaber Hemmati, Mohammad Sina Alikhani , Rasoul Yousefimashouf , Seyyed Hamid Hashemi , Mohammad Yousef Alikhani © ℗
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Background: Infection and inflammation of the meningeal membranes in the brain and spinal cord is called meningitis. The causes of this disease are very diverse, but among the infectious causes of this disease are viruses, bacteria, parasites, and fungi. The aim of this study is to detect bacterial infections causing meningitis by molecular PCR method in cerebrospinal fluid (CSF) samples of hospitalized patients suspected of having meningitis and compare it with the culture results in the laboratories of Hamadan hospitals. Methods: This cross-sectional study was conducted on 104 CSF samples of hospitalized patients suspected to meningitis in the educational hospitals of Hamadan University of medical sciences. The Culture and PCR methods were used to detect the most common causes of bacterial meningitis included Results: The average age of the patients in this study was 31.57 ± 25.85 years. Of the participants 53.85% were male and 46.15% were female. The frequency of detection by culture method for these bacteria was zero and by PCR it was 4.81%. Conclusion: The results of this study showed the low prevalence of common bacterial infections in CSF samples and also showed that the molecular method is more accurate and sensitive compared to culture. Therefore, it is suggested that if meningitis is suspected, clinical experts should check all the factors and use newer diagnostic methods.
کلمات کلیدی
CSF, PCR, Meningitis, Haemophilus influenzae type b, Listeria monocytogenes, Streptococcus agalactiae, Neisseria meningitides, E. coli K1, Streptococcus pneumonia
