مقاومت آنتی بیوتیکی انتروکوکوس فکالیس جدا شده از بخش ICU بیمارستان های شهر همدان

سما مکاری ℗, محمد طاهری ©, مرضیه عسگری نیا

مقاومت آنتی بیوتیکی انتروکوکوس فکالیس جدا شده از بخش ICU بیمارستان های شهر همدان

کد: G-1175

نویسندگان: سما مکاری ℗, محمد طاهری ©, مرضیه عسگری نیا

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خلاصه مقاله

Introduction: Enterococcus faecalis is a bacterium commonly associated with hospital-acquired infections, particularly in intensive care units (ICUs). Due to its ability to acquire resistance to a broad range of antibiotics, it presents a significant challenge in healthcare settings. This study aimed to evaluate the antibiotic resistance patterns of Enterococcus faecalis isolated from ICU patients in hospitals across Hamadan. Methods: In this cross-sectional study, samples of Enterococcus faecalis were collected over a six-month period from ICU patients in three major hospitals in Hamadan. After identification and confirmation of the bacterial species using standard microbiological techniques, antibiotic susceptibility testing was performed using the Kirby-Bauer disk diffusion method. The antibiotics tested included vancomycin, ampicillin, ciprofloxacin, tetracycline, and gentamicin. Results: The results revealed that 70% of Enterococcus faecalis isolates were resistant to ampicillin, and 50% exhibited resistance to vancomycin. Additionally, 60% of the samples were resistant to ciprofloxacin. None of the isolates showed complete resistance to gentamicin, but 40% were resistant to tetracycline. Moreover, multidrug resistance (MDR) was observed in 45% of the isolates. Conclusion: The high level of antibiotic resistance observed in Enterococcus faecalis, especially within ICU settings in Hamadan, is a serious concern that requires immediate intervention to control and prevent the spread of this bacterium. It is essential to implement stricter monitoring and appropriate antibiotic usage in these environments to reduce resistance rates. Further studies with larger sample sizes and investigations into factors contributing to drug resistance are recommended.

کلمات کلیدی

Enterococcus faecalis, Antibiotic resistance

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