Innovative κ–Carrageenan/Locust Bean Gum/Cranberry Extract Wound Dressing for Real-Time Monitoring of Bacterial Infections
کد: G-1188
نویسندگان: Marzieh Askarinia ℗, Mohammad Taheri ©
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Introduction: Chronic wound infections pose significant challenges in clinical treatment, especially with the rise of antibiotic resistance. Recent advancements in biomaterial science have led to the development of smart wound dressings capable of both detecting and treating infections. This systematic review explores the efficacy of wound dressings formulated with κ–carrageenan, locust bean gum, and cranberry extract in monitoring and managing bacterial infections. Methods: A literature search was conducted using PubMed, Scopus, and Web of Science to identify studies published between 2012 and 2023 that focus on smart wound dressings incorporating natural biopolymers and antimicrobial agents. The search terms included "κ–carrageenan," "locust bean gum," "cranberry extract," "wound dressing," and "bacterial infection." Inclusion criteria were studies reporting antimicrobial activity, infection monitoring capabilities, and clinical outcomes related to wound healing. Results: The review found that κ–carrageenan-based dressings exhibited strong antimicrobial properties, primarily against Gram-positive bacteria. Cranberry extract, with its high phenolic content, enhanced the antimicrobial efficacy by disrupting bacterial biofilms. Locust bean gum contributed to the structural integrity and moisture retention of the dressing, promoting faster wound healing. The combination of these materials also enabled real-time monitoring of wound conditions, using colorimetric changes in response to bacterial growth. Conclusion: κ–carrageenan/locust bean gum/cranberry extract wound dressings demonstrate significant potential for managing chronic wound infections. Their dual function of bacterial detection and eradication makes them promising candidates for further research and clinical application.
کلمات کلیدی
Wound Dressing , Bacterial Infections
