بررسی میکروارگانیسم های شایع جدا شده از بیماران ICU بیمارستانی در شمال شرق ایران و الگوی مقاومت آنتی بیوتیکی آن ها
کد: G-1020
نویسندگان: Zahra Mobarezi ℗, Mohammad Derakhshan, Atefeh Aghighi, Majid Khadem-Rezaiyan, Masoud Youssefi ©
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Aims: Microbial infection is the main cause of mortality among patients hospitalized in the ICU. This study aimed to determine the frequency of microorganisms isolated from ICU patients and to assess the antibiotic resistance pattern. Methods: The study analyzed 6,462 culture samples taken from ICU patients. Among the studied cultures, 2302 were positive for microorganisms (35.6%). The bacteria were identified based on CLSI standard guidelines. All ICU culture samples were analyzed for sample sources, identified microorganisms, and antibiotic resistance patterns using SPSS software. Findings: Among the isolated bacteria in the ICU, the most common pathogens were Acinetobacter (34%), Klebsiella pneumoniae (28.6%), and Pseudomonas aeruginosa (12.7%). Most isolated Acinetobacter spp (93.4%), Staphylococcus epidermidis (84.6%), and Stenotrophomonas (80%) were resistant to the available antibiotics used in the disk diffusion method. The lowest resistance was observed in Staphylococcus aureus (44.7%), Klebsiella oxytoca (50%), and Escherichia coli (60.3%). During the study, total antibiotic resistance increased from 75.6% in 2018 to 83.5% in 2019. Conclusion: Our findings indicate that Acinetobacter, Klebsiella pneumoniae, and Pseudomonas aeruginosa are the most prevalent pathogens in the studied ICU. Although hospital-acquired Acinetobacter species are well-known for their significant antibiotic resistance, the bacteria are still highly susceptible to doxycycline. Overall, the study highlights high antibiotic resistance in the ICU, with multi-drug-resistant bacteria being particularly prevalent. These findings highlight the life-threatening risk of multidrug-resistant bacterial infections in ICUs and underscore the need for improved infection control policies and strategies.
کلمات کلیدی
Intensive Care Unit, Microbial Drug Resistance, microorganisms
