نانوپزشکی به عنوان یک استراتژی درمانی جدید برای آبله میمون انسانی: مروری روایی

Arastoo Vojdani ℗, Amir Hossein Esfandiari, Hamid Tanzadehpanah, Zahra Meshkat ©

نانوپزشکی به عنوان یک استراتژی درمانی جدید برای آبله میمون انسانی: مروری روایی

کد: G-1205

نویسندگان: Arastoo Vojdani ℗, Amir Hossein Esfandiari, Hamid Tanzadehpanah, Zahra Meshkat ©

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خلاصه مقاله

Background: Human monkeypox, a rare viral illness transmitted from animals to humans, was initially discovered in 1970 and has historically been limited to central and western Africa. While previously considered a mild disease, recent global outbreaks have highlighted its potential for wider spread. This shift underscores the need for increased vigilance and preparedness to address this emerging health threat. Despite the lack of a proven treatment for human monkeypox and ongoing debate about vaccine necessity, nanomedicine research has explored the potential of nanoparticles as a therapeutic option for viral infections like monkeypox. This literature review examines recent advancements in using nanoscale medicine as a novel approach to combat the human monkeypox virus. Methods: The authors conducted a comprehensive search across multiple academic databases, including PubMed, Scopus, Web of Science, and Google Scholar, focusing on peer-reviewed literature. They used a mix of keywords, such as “Monkeypox” and various nanoparticles, to identify articles on nanoparticle treatments for Monkeypox. This careful strategy ensured coverage of relevant research on the topic. Results: considering the lessons learned from the COVID-19 pandemic, a nanomedicine-based preventative strategy for viral diseases like Monkeypox could be a valuable approach. Traditional drug treatments often pose significant risks to public health, such as drug resistance and adverse side effects. Nanomedicines, utilizing nanomaterials, offer potential advantages over conventional therapies. For instance, silver nanoparticles coated with simple polysaccharides could be explored as a potential treatment. Additionally, targeting the virus with multivalent nanomaterials, which have a stronger affinity for target molecules than monovalent ligands, could be beneficial. These multivalent interactions are crucial for biological processes like signal processing, adhesion, and recognition. Conclusion: In summary, Given the limited therapeutic options for Monkeypox, nanoparticle technology offers a promising avenue. Increased investment in nanoparticle research is essential to explore its potential applications for Monkeypox management and treatment. By understanding nanoparticle properties, researchers may develop novel approaches to enhance existing protocols or create new therapies, ultimately improving patient outcomes.

کلمات کلیدی

Human Monkeypox, nanomedicine, viral infections, viral illness

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