مروری سیستماتیک بر نقش تجهیزات پزشکی مبتنی بر پلی یورتان در پیشگیری از عفونت های بیمارستانی در مقایسه با تجهیزات پزشکی ساخته شده از سایر مواد شیمیایی
کد: G-1231
نویسندگان: معین خدیوزاده ℗, سید عمادالدین شاکری ©
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
The role of polyurethane based medical equipment in preventing nosocomial infections in comparison with medical equipment made of other chemicals, a systematic review Abstract Introduction: Nosocomial infections, particularly those associated with medical equipment is an important concern in medical and healthcare system. This systematic review was conducted to determine the effects of polyurethane (PU) based medical equipment on frequency of nosocomial infections compared to equipment made of other chemicals such as PVC and silicone. Methods: A comprehensive literature search was conducted across PubMed, Scopus and Chemical Abstracts databases for clinical trials and laboratory studies published up to 2023. Inclusion criteria focused on studies comparing the bacterial adhesion rates, biofilm formation, inflammatory responses and clinical infectious outcomes associated with polyurethane medical equipment versus those made of PVC, silicone or other materials. Results: A total of 18 studies met the inclusion criteria, including over 3,000 patients. The systematic review revealed that polyurethane catheters significantly reduced the incidence of urinary tract infections compared to silicone catheters and polyvinyl chloride (PVC) catheters. This advantages was revealed for PU-based implants such as craniofacial implants. Polyurethane based surfaces treated with antimicrobial agents showed a significant decrease in bacterial colonization (90%) compared to untreated surfaces. The study showed that in PU based equipment, the surface' formation of biofilm significantly decreases compared to PVC and silicone base chemicals. The results revealed the polyurethane based equipment, also enhances the biocompatibility with the human body, which decreases the need to subsequent surgeries and the risk of surgery related infections for equipment removal. Conclusion: This study showed that medical equipment made of polyurethane demonstrates superior efficacy in reducing bacterial colonization and, are more effective in preventing nosocomial infections compared to other materials like PVC and silicone. Future research should focus on exploring long-term effects, optimizing these properties and providing more evidences for selection of best materials in medical device manufacturing.
کلمات کلیدی
nosocomial infections , polyurethane , medical equipment
