بررسی اثر بخشی و ارزیابی اثرات جانبی ناشی از واکسیناسیون کووید-19 در مبتلایان به انواع کم کاری یا پرکاری تیروئید
کد: G-1004
نویسندگان: Sadaf Asaei ℗, Marzieh Jamalidoust ©, Sepideh Saeb , Marzieh Hosseini , Mandana Namayandeh , Rosemina Bahrololoom , Nahid Heydari , Ali Hadipour
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دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Introduction: In the last three years, the pandemic has had major effects on the health of people around the world. This has especially affected individuals who already have other medical conditions, like people with thyroid disorders. Vaccination is so important for this group, and the long-term impacts of inoculation and its security on the well-being of these patients will proceed to be uncovered. Therefore, risks related to vaccination and immune response need to be assessed. This study aimed to characterize the immune response, short-term safety, and the effects of multiple variables on these factors after COVID-19 vaccination among people with thyroid abnormalities. Methods: In total, 56 patients (mean age: 37.7±12.6 years old) participated in the study; they had thyroid abnormalities, had received at least one dose of the COVID-19 vaccine, and were usually referred to outpatient clinics for periodical tests. We evaluated the short-term effect and humoral SARS-COV-2 anti-RBD IgG response using a questionnaire and immunoassay, respectively. Results: It should be noted that no significant adverse events were recorded, but running noise (19.6%), low-grade fever (22.2%), loss of smell (17.9%), and Myalgia/body pain (17.9%) were the most common adverse events. The type of vaccine did not show any notable variation in the occurrence of side effects and humoral response. Conclusion: Our study showed that patients with controlled hypothyroidism and hyperthyroidism did not have a higher rate of COVID-19 prevalence, nor did they have a worse prognosis when infected with the virus.
کلمات کلیدی
Thyroid disorders, COVID-19, vaccine, disease-modifying therapy, safety, immunity