بررسی تاثیرات باقیمانده انتی بیوتیک های موجود در غذا بر میکرفلور روده ها، یک مطالعه نظام مند

بررسی تاثیرات باقیمانده انتی بیوتیک های موجود در غذا بر میکرفلور روده ها، یک مطالعه نظام مند

کد: G-1052

نویسندگان: ملینا صدیق ارا ℗, پریسا صدیق ارا ©

زمان بندی: زمان بندی نشده!

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خلاصه مقاله

Introduction: Gut microbiota may change following changes in diet or exposure to drugs. Humans can be exposed to antibiotic residues in food. People may be exposed to these compounds for years. But in calculating the maximum residue level (MRL), the effects of antibiotic residues on the intestinal microbiota have not been investigated. Some evidence shows that even at low doses of antibiotics lead to changes in the gut microbiota. Therefore, a systematic study was conducted with the aim of investigating the effect of antibiotic residues in food on intestinal microbiota. Method: The main criterion of this research was to investigate the effects of antibiotics at low doses. For this purpose, a database search was conducted with the keywords antibiotic, veterinary antibiotic, food, residue, microbiome and microbiota. The tested doses of each antibiotic in the studies were compared with their MRL in food. Findings: The most changes in the structure and function of microbiota were related to tetracycline, sulfamethoxazole, cefquinome, florfenicol and tylosin. The lowest observed effect was related to fosfomycin and amoxicillin antibiotics. Discussion: Exposure to antibiotic residues through food is usually a long-term exposure. Gut microbiota may be altered following food containing residue of antibiotics at a minimum dose in this long-term exposure. Therefore, it is necessary to inform breeders and competent authorities in order to comply with the principles of treatment.

کلمات کلیدی

food, antibiotic, ,microbiota

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