نقش آنمی دوران بارداری در عفونت بیمارستانی مادر در طی زایمان و پس از آن، یک مطالعه مرور سیستماتیک و متاآنالیز

طلعت خدیوزاده © ℗, سپیده رضایی

نقش آنمی دوران بارداری در عفونت بیمارستانی مادر در طی زایمان و پس از آن، یک مطالعه مرور سیستماتیک و متاآنالیز

کد: G-1139

نویسندگان: طلعت خدیوزاده © ℗, سپیده رضایی

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خلاصه مقاله

Background and aim: Iron deficiency anemia is the most common cause of anemia during pregnancy and is associated with adverse maternal and neonatal outcomes. This meta-analysis was done to determine the role of prenatal anemia on the risk of maternal nosocomial infection during and after delivery. Methods A systematic review was performed, analyzing studies that were done on the prevalence of prenatal anemia and its relationship with nosocomial infections. Data were extracted using a widespread literature search across various databases, including PubMed, EMBASE, and Scopus, from 2001 to June 2023, directing on maternal characteristics, infection rates and relevant outcomes. The risk of bias in these studies was assessed with the Newcastle-Ottawa Quality Assessment (NOS) tool. Statistical analyses were performed to determine the odds ratios (OR) for infection risk in anemic versus non-anemic mothers. Results: The eligible studies involving 1012 mothers. Prenatal anemia significantly increased the risk of nosocomial infections, with an odds ratio of 1.686 (95% CI: 1.217-2.298) compared to non-anemic women. Other factors such as gestational age, delivery type (caesarean section), and duration of hospitalization were identified as contributing factors that increase the risk. It is worth-noting that after childbirth, anemia worsens following postpartum hemorrhage and reduces the mother's immunity, leading to more susceptibility to infections. Conclusion: The study addresses anemia as an important preventable factor in maternal health strategies, shows the vital need for its screening and treatment during pregnancy to reduce the risk of nosocomial infections during and after the childbirth and highlights the multifactorial nature of risk factors. Advanced nutritional and prenatal care interventions are essential to prevent anemia and infection in pregnant mothers.

کلمات کلیدی

prenatal, anemia, nosocomial infection, childbirth, systematic review, meta-analysis

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