بررسی تاثیر پروبیوتیکها بر مشکلات عفونی در بیماران سرطانی: یک مرور سیستماتیک
کد: G-1201
نویسندگان: Mohammad Chahkandi © ℗, Farzaneh Pardehshenas
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Introduction: Immunosuppression is one of the most dangerous complications of cancer treatments, leading to increased susceptibility to infections that can diminish patients' chances of recovery and survival. The use of probiotics as a natural solution improves microbial balance and enhances immune response, which may help reduce infectious complications in these patients. This study aims to examine the effect of probiotics on infectious problems in cancer patients. Search Strategy: This study was conducted according to the PRISMA 2020 guidelines. initial search using the keywords "probiotic", "cancer", "neoplasms", and "infection" in the databases PubMed, Magiran, and the Google Scholar search engine yielded 83 articles. Inclusion criteria involved clinical trials focused on controlling infections in cancer patients using probiotics, published between 2014 to 2024, while exclusion criteria included any deviation from these parameters. After eliminating duplicates and irrelevant studies, 7 articles were analyzed. Results: The review conducted three studies showing the impact of probiotic use in reducing postoperative infections, and inflammatory indicators, and improving short-term clinical outcomes in colorectal and gastric cancer. While one study comparing probiotics with antibiotics as prophylaxis for postoperative infections, suggested the use of antibiotics. another study demonstrated a reduction in oral candidiasis in patients undergoing head and neck radiotherapy with probiotics, whereas a different study in the same patient group did not report a significant effect on the oral microbiota. One study showed a reduction in urinary tract infections (UTIs) after cystoscopy with the use of probiotics in patients with bladder cancer. Conclusion: Despite varying results, it appears that the use of probiotics may serve as an effective method for reducing infectious complications in Surgical site, urinary tract and mouth arising from cancer treatments. Future studies should specifically focus on the type and dosage of probiotics, infectious agents, and the safety of these approaches.
کلمات کلیدی
cancer, neoplasms, infection, probiotic
