عفونت های اسینتوباکتر در بیماران اطفال: اپیدمیولوژی و تجزیه و تحلیل مقاومت دارویی در بخش های مراقبت ویژه از یک مرکز طبی کودکان شرق ایران برای دو سال متوالی
کد: G-1059
نویسندگان: خیزران میری ©, تکتم اعتضادی ℗
زمان بندی: زمان بندی نشده!
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Abstract Background This study aims to investigate the epidemiology of Acinetobacter infections and analyze the patterns of drug resistance in pediatric patients admitted to intensive care units (ICUs) at a children's medical center in Eastern Iran over a two-year period. Method A retrospective analysis was conducted on pediatric patients diagnosed with Acinetobacter infections in the ICUs between 2022 and 2024. Data on demographic characteristics, clinical presentation, laboratory results, treatment regimens, and outcomes were collected. Antimicrobial susceptibility testing was performed using standard methods to assess the resistance profiles of the isolated strains Result: A total of 78 patients with confirmed Acinetobacter infections were identified. The majority were under four years old, with a higher prevalence in females. The most common clinical manifestations included pneumonia, bloodstream infections, and urinary tract infections. The analysis revealed a significant increase in resistance rates to commonly used antibiotics, particularly to 3th and 4th generation cephalosporines ,carbapenems and fluoroquinolones (90%). Multidrug-resistant (MDR) strains accounted for 91% of the isolates, complicating treatment options. Conclusion: Acinetobacter infections pose significant challenge in pediatric ICUs, with rising drug resistance trends observed over the two-year study period. The high prevalence of multidrug-resistant strains underscores the urgent need for enhanced infection control measures, continuous surveillance, and the development of targeted therapeutic strategies. This study highlights the importance of ongoing epidemiological research to inform clinical practices and improve patient outcomes in this vulnerable population. Further investigations are recommended to explore the mechanisms underlying resistance and to evaluate the effectiveness of new treatment protocols.
کلمات کلیدی
Keywords: Acinetobacter infections pose, in Pediatric Patients, ICU
